floridarest.blogg.se - Cashew shell

The present chapter deals with the source of production, processes, and geographical information, export/import, and chemical composition, industrial utility, and environmental effects of CNSL in modern perspectives. Other components include 1241-hydroxy-2-carboxy-3-pentadecyl benzene, 1-hydroxy-2-carboxy-3-(8’-pentadecenyl) benzene, 1-hydroxy-2-carboxy-3-(8,’11’-pentadecadienyl) benzene, 1-hydroxy-2-carboxy-3-(8,’11,’14’-pentadecatrienyl)benzene, 2-methyl-5-pentadecyl resorcinol, 2-methyl-5-(8’-pentadecenyl)resorcinol, 2-methyl-5-(8,’11’-pentadecadienyl) resorcinol, 2-methyl-5-(8,’11,’14’-pentadecatrienyl)resorcinol, 3-pentadeca-anisole, 3-(8’-pentadecenyl) anisole, 1-methoxy-3-(8,’11’-pentadecadienyl)benzene, 1-methoxy-3-(8,’ 11,’14’-pentadecatrienyl)benzene, 5-pentadecyl resorcinol, 5-(8’-pentadecyl) resorcinol, 5-(8,’11’-pentadecadienyl)resorcinol, and 5-(8,’ 11,’14’-pentadecatrienyl)resorcinol. The cashew tree consists of the cashew nut fruit (which is a curved edible seed, housed in a honeycomb-like shell), the apple, leaf, and bark.

This oil is composed of anacardic acid (3-n-pentadecylsalicylic acid), and lesser amounts of cardanol (3-n-pentadecylphenol), cardol (5-n-pentadecylresorcinol), methylcardol (2-methyl-5-n-pentadecylresorcinol) and a small amount of polymeric material. The shell of the cashew nut (Anacardium occidentale L.) contains an alkylphenolic oil named cashew nut shell liquid (CNSL) amounting to nearly 25% of the total weight of the nut. By weight, cashew nuts comprise 50% shell, 25% kernel (including testa), and 25% shell liquid. The fruit consists of an outer shell, inner shell, and the kernel.

Joining Sriram for the study were Asa Ljunggren-Rose, Chandramohan Natarajan, Pranathi Matta, Akansha Pandey and Isha Upender.The cashew tree consists of the cashew nut fruit (which is a curved edible seed, housed in a honeycomb-like shell), the apple, leaf, and bark. "These are striking results that clearly urge further study of anarcardic acid for demyelinating diseases," Sriram said. The cashew shell waste generated in small-scale cashew processing industries was found to be 67.5 of total weight of cashew seed, which can be utilized as fuel.

In an animal model of demyelination treated with the compound, dissection and electron microscopy showed dose-dependent increases in myelination.

In two animal models of demyelination, treatment with the compound increased the relative presence of IL-33-expressing OPCs and led to reduced paralysis.

In vitro, the addition of the compound to rat cells most responsible for myelination - oligodendrocyte precursor cells, or OPCs - spurred induction of IL-33 and rapidly increased the expression of myelin genes and proteins, including dose-dependent increases in myelin basic protein.

The report includes a range of new findings that point to potential therapeutic use of anacardic acid for demyelinating diseases: Sriram and team grew interested in it because it's known to inhibit an enzyme involved in gene expression called histone acetyltransferase, or HAT, and the team had discovered that whatever inhibits HAT induces production of IL-33. The cashew shell compound is called anacardic acid. IL-33 is, among other things, an immune response regulator, and multiple sclerosis is an autoimmune disorder. Previous work led by Sriram showed that a protein called interleukin 33, or IL-33, induced myelin formation. Weaver III Professor of Neurology and chief of the Division of Neuroimmunology.

"We see this as an exciting finding, suggesting a new avenue in the search for therapies to correct the ravages of MS and other demyelinating diseases," said the paper's senior author, Subramaniam Sriram, MBBS, William C. We render high quality CNSL Oil in UK, USA. Damage to this covering - demyelination - is a hallmark of multiple sclerosis and related diseases of the central nervous system. Cashew Nut Oil - We are the leading supplier and manufacturer of 100 pure and natural Cashew Nut Shell Oil.

Myelin is a protective sheath surrounding nerves.